Placental Exosome-Assoicated MicroRNAs in Normal Pregnancy and Preeclampsia
نویسندگان
چکیده
منابع مشابه
Investigation of ANP Plasma Concentration in Normal Pregnancy and Preeclampsia
با وجود شواهد روزافزونی که بیانگر نقش احتمالی ANP در هموستاز طبیعی مایعات بدن است، اما هنوز اهمیت نقش این پیتید در سلامت و بیماری بدرستی مشخص نیست. بر اثر ازدیاد فشار دهلیزی و تعداد انقباضات آن، ANP از میوسیت های دهلیزی ترشح می شود. تزریق مقادیر زیادی از ANP صناعی به انسان و حیوان سبب کاهش فشار سیستمیک دهلیزی و افزایش دفع سدیم و برقراری دیورز می گردد. مطالعات اخیر بر روی تأثیر تزریق ANP صناعی ...
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Glomerular filtration rate and renal plasma flow increase by 40 to 65 and 50 to 85%, respectively, during normal pregnancy in women. Studies using the gravid rat as a model have greatly enhanced our understanding of mechanisms underlying these remarkable changes in the renal circulation during gestation. Hyperfiltration is largely due to increased renal plasma flow, the latter attributable to p...
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One in five pregnant women suffer from gestational complications, prevalently driven by placental malfunction. Using RNASeq, we analyzed differential placental gene expression in cases of normal gestation, late-onset preeclampsia (LO-PE), gestational diabetes (GD) and pregnancies ending with the birth of small-for-gestational-age (SGA) or large-for-gestational-age (LGA) newborns (n = 8/group). ...
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Preeclampsia is associated with increased peripheral resistance. This study was performed to determine whether an increase of venous distensibility occurs as well in preeclampsia. We obtained venous distensibility by measuring the venous pressure-volume relation in the forearm with a water-filled plethysmograph. Twenty-one women with normal pregnancy, 12 women with severe preeclampsia, and 8 wo...
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ژورنال
عنوان ژورنال: Journal of Nippon Medical School
سال: 2011
ISSN: 1345-4676,1347-3409
DOI: 10.1272/jnms.78.48